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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TACC1 All Species: 10.3
Human Site: S454 Identified Species: 22.67
UniProt: O75410 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75410 NP_001116296.1 805 87794 S454 H V N E I L E S P K K A K S R
Chimpanzee Pan troglodytes XP_001171659 806 87880 S455 H V N E I L E S P K K A K S R
Rhesus Macaque Macaca mulatta XP_001094596 713 77960 T382 C K V K K H E T Q S L A L D A
Dog Lupus familis XP_848665 800 87410 S449 H I N E I L E S P K K A K S R
Cat Felis silvestris
Mouse Mus musculus Q6Y685 774 83933 A440 T S S G F C P A T G N H V N E
Rat Rattus norvegicus Q4KLH6 1403 160982 R800 H L M E D I K R L K Q D K Q A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506072 798 87999 A447 E D M K K G K A S P K K A K S
Chicken Gallus gallus XP_428807 620 67438 P289 K V K Q Y E T P A L V L D G C
Frog Xenopus laevis Q9PTG8 931 102522 F581 K L A T E A D F L L A A D M D
Zebra Danio Brachydanio rerio XP_694073 852 95238 K501 E K L T E K L K S D G T P E Q
Tiger Blowfish Takifugu rubipres NP_001011696 863 95190 P513 K G S Y T F D P D N F D D S V
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 84.7 85.5 N.A. 73.9 20.8 N.A. 69.8 50 27 42.6 38.8 N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 85.8 91.1 N.A. 81.6 32.6 N.A. 78.1 59 44.1 55 53.8 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 93.3 N.A. 0 26.6 N.A. 6.6 6.6 6.6 0 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 20 53.3 N.A. 26.6 13.3 20 6.6 20 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 10 0 19 10 0 10 46 10 0 19 % A
% Cys: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 10 0 0 10 0 19 0 10 10 0 19 28 10 10 % D
% Glu: 19 0 0 37 19 10 37 0 0 0 0 0 0 10 10 % E
% Phe: 0 0 0 0 10 10 0 10 0 0 10 0 0 0 0 % F
% Gly: 0 10 0 10 0 10 0 0 0 10 10 0 0 10 0 % G
% His: 37 0 0 0 0 10 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 10 0 0 28 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 28 19 10 19 19 10 19 10 0 37 37 10 37 10 0 % K
% Leu: 0 19 10 0 0 28 10 0 19 19 10 10 10 0 0 % L
% Met: 0 0 19 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 28 0 0 0 0 0 0 10 10 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 10 19 28 10 0 0 10 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 10 0 10 0 0 10 10 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 28 % R
% Ser: 0 10 19 0 0 0 0 28 19 10 0 0 0 37 10 % S
% Thr: 10 0 0 19 10 0 10 10 10 0 0 10 0 0 0 % T
% Val: 0 28 10 0 0 0 0 0 0 0 10 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _